BioJapan2023 Exhibition Highlights
| No | Title | Department | Researcher in charge | Comment |
|---|---|---|---|---|
| ① | Introducing the sample grid that dramatically speeds up structural analysis using cryo-EM | Graduate School of Pharmaceutical Sciences | Tsuyoshi INOUE | You can test our performance in a trial collaboration. All of our trial companies have already moved on to joint research. We can propose various forms of collaboration, so please let us know what you would like to do! |
| ② | Introducing a mouse that can KO only specific cells specified by two marker genes at any time | Research Institute for Microbial Disease (RIMD) | masahiro YAMAMOTO | With the advancement of analytical technology, it has become clear that cells that were thought to be single can actually be classified into various subclasses, and research on segmented cells is underway. Since only specific cell lines can be deleted in mice, it can be used in a variety of ways, such as involvement in pathological conditions or construction of disease models. We can propose various forms of collaborative research, so please let us know what you would like to do. |
| ③ | Microbiome: P. copri. isolated from the intestines of rheumatoid arthritis patients]Research Institute for microbial disease: | Research Institute for Microbial Disease (RIMD) | Kiyoshi TAKEDA | We are looking for collaborators on Prevotella copri. that cause excessive immune responses in the intestines of rheumatoid arthritis patients. Although Prevotella copri. are also present in the intestines of healthy individuals, this Prevotella copri. is different at the genomic level. |
| ④ | Introducing antibody drug candidates CKAP4, nucleic acid drug candidates Arl4c and GREB1 in the anti-cancer field | Center for Infectious Disease Education and Research (CIDER) | akira KIKUCHI | Humanized antibodies available. You can also check for synergistic effects with your existing treatments. Arl4c and GREB1, Nucleic acids are east to deliver and effective for liver cancer. |
| ⑤ | Novel low-molecular compound aimed at treating heart failure | Graduate School of Medicine | Osamu TSUKAMOTO | Introducing a group of compounds with cardiac-specific cMLCK activating activity. Omecamtive mecarbil (OM) only increases the generated tension, while cMLCK also increases the rate of contraction, resulting in a potent therapeutic effect. In vitro studies have shown that it improves myocardial sarcomere structure. |
| ⑥ | Nutritional pulse improves intestinal environment | Graduate School of Medicine | Hideshi ISHII | Microbiome: weight loss via changes in gut microbiota due to nutrient restriction |
Contact:
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Kazuhiko MAEKAWA
E-mail: biojapan2023[★]uic.osaka-u.ac.jp
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